Just as the patent is about to run out for Prozac, we learn that this worldwide topselling antidepressant isn’t any more effective than its competitors, Paxil and Zoloft. These three popular antidepressants, all from the same drug class, called selective serotonin reuptake inhibitors (SSRIs), were shown to be of similar effectiveness in a new study published in the Journal of the American Medical Association (JAMA, 12/19/01).
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Antidepressants can help reduce risk of repeat heart attacks and cardiac death, according to a study led by Stanford University researchers published Monday.

The findings suggest that patients who have already had a heart attack and suffer from depression should talk to their doctors about taking antidepressants to prevent another cardiac event.
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A selective serotonin reuptake inhibitor (SSRI) for treating premenstrual dysphoric disorder (PMDD), the second SSRI and second drug approved for this indication.

* Recommended Dosage: 50 mg/day throughout the menstrual cycle or during the luteal phase. If necessary, dose may be increased at 50-mg increments per cycle, up to 150 mg/day when taken throughout the cycle or 100 mg/day when taken during the luteal phase.
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